Effect of bilateral subthalamic nucleus stimulation on parkinsonian gait
نویسندگان
چکیده
منابع مشابه
Effect of bilateral subthalamic nucleus stimulation on gait in Parkinson's disease.
The fundamental disturbance of the parkinsonian gait is the reduction in walking velocity. This is mainly due to reduction in stride length, while cadence (steps/min) is slightly enhanced. Treatment with L-dopa increases stride length while cadence is unchanged. Chronic stimulation of the thalamus has no effect on Parkinsonian gait. The efficacy of electrical stimulation of the subthalamic nucl...
متن کاملResponse to levodopa in parkinsonian patients with bilateral subthalamic nucleus stimulation.
The response to levodopa changes over time in Parkinson's disease, probably due to alterations in the dopaminergic system, progression of the disease and pulsatile oral intake of the drug. Bilateral high-frequency stimulation of the subthalamic nucleus (STN) allows a large reduction or the complete cessation of levodopa intake in patients with advanced Parkinson's disease. We studied variation ...
متن کاملEffect of bilateral deep brain stimulation of the subthalamic nucleus on freezing of gait in Parkinson's disease.
OBJECTIVE A prospective cohort study to evaluate the efficacy of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on freezing of gait (FOG) in patients with advanced Parkinson's disease. METHODS Patients (n = 10) with advanced Parkinson's disease were surgically implanted with microelectrodes to facilitate STN-DBS. Evaluations of FOG, motor function, activities of daily living ...
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BACKGROUND Thalamotomies and pallidotomies were commonly performed before the deep brain stimulation (DBS) era. Although ablative procedures can lead to significant dystonia improvement, longer periods of analysis reveal disease progression and functional deterioration. Today, the same patients seek additional treatment possibilities. METHODS Four patients with generalized dystonia who previo...
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Although a cardinal symptom of Parkinsonian disease, up to now, rigidity has been investigated much less than spasticity in hemiplegic patients. Many pathophysiological mechanisms may at least theoretically contribute to Parkinsonian rigidity, from altered viscoelastic muscle properties to inability of parkinsonian patients to relax. However, as demonstrated many years ago, motoneuron responses...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2001
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s004150170027